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Evaluation of Taste in The Patients with Oral Mucosal Disease by Electrogustomter

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ÀÌ¿ëÇÑ ( Lee Yong-Han ) - ºÎ»ê´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
ÅÂÀÏÈ£ ( Tae Il-Ho ) - ºÎ»ê´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
°í¸í¿¬ ( Ko Myung-Yun ) - ºÎ»ê´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
¾È¿ë¿ì ( An Yong-U ) - ºÎ»ê´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç

Abstract

º» ¿¬±¸ÀÇ ¸ñÀûÀº Àü±â ¹Ì°¢ ÃøÁ¤±â¸¦ »ç¿ëÇÏ¿© ±¸°­Á¡¸·Áúȯ(±¸°­ÆíÆòż±, Àç¹ß¼º ¾ÆÇÁŸ¼º ±Ë¾ç)À» Áö´Ñ ȯÀÚÀÇ ¹Ì°¢ °¨¼ö¼ºÀ» Á¶»çÇϱâ À§ÇÔÀÌ´Ù. 173¸íÀÇ È¯ÀÚ°¡ 100¸íÀÇ ´ëÁ¶±º°ú 73¸íÀÇ ½ÇÇ豺À¸·Î ±¸¼ºµÇ¾úÀ¸¸ç 73¸íÀÇ È¯ÀÚ´Â ºÎ»ê´ëÇÐ º´¿ø ±¸°­³»°ú¿¡ 2005³â 4¿ùºÎÅÍ 2007³â 1¿ù±îÁö ³»¿øÇÏ¿´´Ù. ´ëÁ¶±ºÀº 2006³â 2¿ùºÎÅÍ 8¿ù±îÁö ûÁÖ ¹× ÀÎõ ¼ÒÀç Ä¡°úÀÇ ¿ø¿¡ ³»¿øÇÑ Ä¡°úȯÀÚ¸¦ ´ë»óÀ¸·Î ÇÏ¿´´Ù. Àü±â¹Ì°¢ÃøÁ¤±â(electrogustometer)¸¦ »ç¿ëÇÏ¿©, ¿À¸¥ÂÊ Çô³¡, Ãø¹æ Áß¾ÓºÎÀ§, À¯°ûÀ¯µÎ ±ÙóºÎÀ§, ¿¬±¸°³ºÎÀ§¿¡ ¹Ì°¢ÃøÁ¤À» ½ÃÇàÇÏ¿´À¸¸ç ±× °á°ú´Â ´ÙÀ½°ú °°´Ù.
1. ½ÇÇ豺¿¡¼­ÀÇ Àü±â ¹Ì°¢ ¿ªÄ¡´Â ´ëÁ¶±º¿¡¼­ º¸´Ù À¯ÀÇÇÏ°Ô ³·Àº ¼öÄ¡¸¦ ³ªÅ¸³»¾ú´Ù(p£¼0.001).
2. ½ÇÇ豺¿¡¼­ ¸¸¼ºµµ¿Í º´¼ÒÀÇ °³¼ö¿¡ µû¸¥ Àü±â ¹Ì°¢ ¿ªÄ¡ÀÇ ÁÖ¸ñÇÒ ¸¸ÇÑ º¯È­´Â °üÂûµÇÁö ¾Ê¾Ò´Ù.
3. DexanÀ» ´Üµ¶ »ç¿ëÇßÀ» ¶§¿Í Dexan°ú PrednisoloneÀ» ÇÔ²² Åõ¿©ÇÑ È¯Àڵ鿡¼­, Àü±â ¹Ì°¢ ¿ªÄ¡ÀÇ ÁÖ¸ñÇÒ ¸¸ÇÑ º¯È­´Â °üÂûµÇÁö ¾Ê¾Ò´Ù.
4. Ä¡·á °æ°ú(¹ÝÀÀ¾øÀ½ vs 1/2 °³¼± vs ¿ÏÀü°³¼±)¿¡ µû¸¥ Àü±â ¹Ì°¢ ¿ªÄ¡ÀÇ ÁÖ¸ñÇÒ¸¸ÇÑ º¯È­´Â ¾ø¾ú´Ù. ±×·¯³ª NAS¿¡ ÀÇÇØ ÃøÁ¤µÈ Áõ»óÀÇ °³ÀÎÀû ÁöÇ¥´Â ¹Ì¹ÝÀÀ ±º¿¡¼­´Â ÁÖ¸ñÇÒ Á¤µµ·Î Áõ°¡ÇÏ¿´À¸¸ç ¿ÏÀü °³¼± ±º¿¡¼­´Â ´«¿¡ ¶ç°Ô °¨¼ÒÇÏ¿´´Ù (p£¼0.001)

The purpose of this study was to investigate the taste sensitivity in patients with oral mucosal diseases(Oral lichen planus(OLP), Recurrent apthous ulcer(RAU)) using electrogustometer. One hundred and seventy three subjects were included for the study and they were categorized into 2 groups (control 100, patient 73) and patient group was investigated in the Department of Oral Medicine, Pusan National University Hospital from April, 2005 until January, 2007. Control group was investigated in the clinics at Inchen Metroplitan city and Cheongju city from February to August, 2006. The electrical taste thresholds were measured by using an electrogustometer for the 4 different sites (tongue tip, tongue lateral, circumvallate papilla and soft palate) in oral cavity.
The results were as follows;
1. The electrical taste threshold in patient group was significantly decreased than that in the control group(p£¼0.001).
2. The electrical taste threshold, in terms of the chronicity and lesion multiplicity, was not significantly changed in patient group.
3. The electrical taste threshold was not significantly changed in Dexan only and Dexan£«Prs combination treated group.
4. The electrical taste threshold, in terms of treatment progress/no response vs half response vs complete response), was not significantly changed. However subjective index which was determined by NAS(Numerical Analogy Scale) was significantly increased in no response group but significantly decreased in complete response group(p£¼0.001)

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Àü±â¹Ì°¢ ¿ªÄ¡;Àü±â ¹Ì°¢ ÃøÁ¤±â;±¸°­ÆíÆòż±;Àç¹ß¼º ¾ÆÇÁŸ¼º ±Ë¾ç
electrical taste threshold;electrogustometer;OLP;RAU

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